University:
Western Sydney University
Course:
MEDI 2003 | Clinical Sciences 2
Academic year:

2024
Views:

490

Pages:

1
Author:

Mariam A. A.

One gene-one enzyme hypothesis/ one gene-one protein hypothesis The one gene–one enzyme hypothesis is the idea that genes act through the production of enzymes, with each gene responsible for producing a single enzyme that in turn affects a single step in a metabolic pathway Issues with the one gene-one enzyme hypothesis/ one gene-one protein hypothesis • Their theory said that an enzyme or a protein is formed by only one gene. But later studies showed that an enzyme or a protein, e.g., haemoglobin protein is formed by more than one gene. As a result, it was modified one gene – one polypeptide’ where one gene codes for one polypeptide. Later discoveries revealed that some proteins require more than one polypeptide. For example, each haemoglobin protein in a red blood cell that has four polypeptide chains. Therefore, Beadle and Tatum’s hypothesis was modified to be known as the ‘one gene – one polypeptide’ hypothesis. - The hypothesis that a large class of structural genes exists in which each gene encodes a single polypeptide, which may function either independently or as a subunit of a more complex protein What is the difference between the first and second hypothesis? _________________________________________________________________________________ _________________________________________________________________________________ _________________________________________________________________________________