Diseases of Renal Arteries - Edubirdie

University:
Western Sydney University
Course:
MEDI 2003 | Clinical Sciences 2
Academic year:

2024
Views:

252

Pages:

2
Author:

Mariam A.

Diseases of Renal Arteries    Dissection of the aorta – e.g. a rip or tear at the lining of the aorta, which results in blood accumulating at the external surface of the vessels and eventually compressing against the vessel causing limitation in blood flow o Hypertensive syndromes o Marfans syndrome o Atherosclerosis Renal artery stenosis Renal artery embolus (Whole artery, Segmental infarction) Atherosclerotic Disease    Tend to occur in older people Vascular risk factors (especially diabetes mellitus) Tend to affect proximal third of renal artery Fibromuscular Dysplasia     Tend to occur in younger people More frequent in females than males Tend to affect distal two-thirds of renal artery Slow progression with good response to treatment Hormonal and Haemodynamic Consequences of Renovascular Disease     Affected kidney detects the reduction in blood flow and thus activates the RAAS + sympathetic nervous system Increases its production of renin from the glomerular apparatus of the kidney + release of other vasoconstrictors Activation of a cascade of enzymatic reactions eventually leading to production of aldosterone o Aldosterone causes an increase in salt retention, which leads to increased fluid retention due to osmotic effects Leads to a variety of complications such as hypertension and pulmonary oedema

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