University:
Eastern Kentucky University
Course:
BIO 273 | Clinical Microbiology
Academic year:

2022
Views:

124

Pages:

1
Author:

folclord7m

Pseudomonas Aeruginosa (-) Features: 1. Oxidase (+) 2. Catalase (+) 3. Blue-green pigment is produced from: a. Pyocyanin b. Pyoverdin 4. Thrives in aquatic environment 5. Fruity grape-like odor 6. Encapsulated 7. Obligate aerobe (other enterobacteriaciae are mostly facultative anaerobes) Pathogenesis: 1. Exotoxin A a. EF-2 inhibition by ribosylation Diseases: 1. Nosocomial Pneumonia a. #1 cause of nosocomial gram negative pneumonia 2. Nosocomial UTIs 3. Pulmonary infections in cystic fibrosis patients a. #1 cause of respiratory failure in CF patients 4. Burn patients a. Fatal complications produced 5. Hot Tub Folliculitis 6. Ecthyma gangrenosum a. Pseudomonas gets into blood and causes sepsis and release toxins b. This leads to black necrotic skin lesions 7. Osteomyelitis a. Common in i. DM patients ii. IV drug users 8. Otitis Externa Treatment: 1. Piperacillin 2. Flouroquinolones (UTIs) 3. Aminoglycosides (in combination with beta lactam drugs)