University:
Eastern Kentucky University
Course:
BIO 273 | Clinical Microbiology
Academic year:

2022
Views:

241

Pages:

2
Author:

rehinhea0c

E. Coli (-) Features: 1. Ferments lactose a. Pink colonies on McConkey agar 2. Fimbriae 3. Green sheen on Eosin Methyline Blue (EMB) agar 4. Encapsulated a. K antigen on capsule is helpful in serotyping 5. Catalase (+) 6. #1 cause of UTIs 7. Sepsis (by LPS endotoxin in outer cell membrane) 8. Neonatal meningitis (only if it has K antigen) Types: 1. Entero hemorrhagic E. coli (EHEC) 2. Entero toxinogenic E. coli (ETEC) EHEC: Features: 1. Only EHEC doesn’t ferment sorbitol Transmission: 1. Eating undercooked hamburger Pathogenesis: 1. Produces shiga-like toxin a. Binds to 60S subunit of ribosome Diseases: 1. Bloody diarrhea 2. HUS in patients under the age of 10 a. Caused by O157:H7 serotype ETEC: Features: 1. Traveler’s diarrhea Transmission: 1. Via water sources 2. Classical history presentation includes recent travel to Mexico Pathogenesis: It produces two types of toxins: 1. Heat labile toxin a. Increases cAMP (acts like cholera) 2. Heat stable toxin a. Increases cGMP Diseases: 1. Watery diarrhea