University:
Eastern Kentucky University
Course:
BIO 273 | Clinical Microbiology
Academic year:

2022
Views:

354

Pages:

2
Author:

kundgetanufv

Yersinia (-) Yersinia Enterocolitica: Features: 1. Cold growth 2. Bipolar (safety pin) staining 3. Encapsulated Transmission: 1. Puppy feces 2. Contaminated milk products a. Toddlers are commonly affected Diseases: 1. Invasive infection a. Fever b. Leukocytosis c. Abscesses d. Intestinal perforation e. Paralytic ileus f. Necrotic small bowel 2. Mimics appendicitis 3. Bloody diarrhea Yersinia Pestis: Features: 1. Bipolar (safety pin) staining 2. Cause of bubonic plague Reservoir: 1. Prairie dogs Transmission: 1. Flea bites Pathogenesis: 1. Endotoxin a. DIC i. Leads to necrosis of digits and other appendages 2. Exotoxins 3. Yersinia associated outer proteins (YOPS) a. Macrophage and neutrophil dysfunction by inhibiting phagocytosis and cytokine production i. Hence, Yersinia spreads and replicates easily b. Secreted by type 3 secretion system Prevention: 1. Killed Vaccine Treatment: 1. Streptomycin + tetracycline 40