University:
Eastern Kentucky University
Course:
BIO 273 | Clinical Microbiology
Academic year:

2022
Views:

43

Pages:

3
Author:

Accinkiquicpqw

Paramyxovirus Features: 1. Enveloped 2. Important viruses of the family are: a. Measles virus b. Mumps virus c. Respiratory syncytial virus (RSV) d. Parainfluenza virus Pathogenesis: Viruses in paramyxovirus family can have one or all of the following virulence factors: 1. Hemogluttinin (HA) 2. Neuraminidase (NA) 3. Fusion Proteins a. Plays a role in creation of multinucleated giant cells Me Measl asl asles es Vi Virus: rus: Transmission: Respiratory droplets Diseases: Measles is also called Rubeola. Symptoms are as follows: 1. Prodermal symptoms (4 C’s): a. Cough b. Coryza c. Conjunctivitis d. Koplik spots Fever is also associated. The other symptoms include: 2. Rash a. Starts on face and moves downward b. Confluent rash 3. Pneumonia a. Complication of measles infection 4. Subacute Sclerosing Pan Encephalitis (SSPE) a. Inflammation and sclerosis of brain Pathogenesis: Has following virulence factors: 1. Hemogluttinin 2. Fusion proteins Prevention: 1. MMR a. Live attenuated vaccine b. Contraindicated in pregnancy 2. Vitamin A reduces measles morbidity and mortality Mu Mumps mps Virus Virus:: It causes: 1. Parotitis 2. Orchitis a. Mostly unilateral b. Testicular atrophy c. Impaired fertility (but not total sterility) 3. Meningitis Pathogenesis: It has following virulence factors: 1. Hemogluttinin 2. Neuraminidase 3. Fusion proteins RSSV: RSV It is commonly seen in infants with age <6 months Pathogenesis: 1. Virus attaches to G protein to infect respiratory endothelium 2. Virulence factors: a. Fusion proteins Diseases: 1. Bronchiolitis 2. Pneumonia 3. Rhinitis a. #1 cause in infants 4. Pharyngitis a. #1 cause in infants Treatment: 1. Ribavirin a. Contraindicated in pregnant women and infants 2. Palivizumab a. Used primarily in prevention Pa Parain rain rainflue flue fluenza nza V Virus: irus: It causes Croup. The other names of this disease are: 1. Laryngotracheobronchitis 2. Seal bark cough 3. Inspiratory stridor Pathogenesis: The virulence factors are: 1. Hemogluttinin 2. Neuraminidase 3. Fusion proteins Lab Diagnosis: Steeple sign on X-ray.