University:
California State University, Northridge
Course:
BIOL 101 | General Biology
Academic year:

2022
Views:

345

Pages:

30
Author:

Im Tiger

INDEX 1. Certificate 2. Acknowledgment 3. Introduction 4. Historical background 5. Biological material used '6. Approaches used for DNA fingerprinting 7. Applications of DNA fingerprinting 8. Famous cases solved 9. Conclusion 10. Bibliography CERTIFICATE This is to certify that this biology Investigatory has been Project on the topic successfully completed by................of class under the guidance of .............in particular fulfilment of the curriculum of central Board of Secondary Education (CBSE) leading to annual Examination of year ...... Teacher incharge External examiner ACKNOWLEDGMENT As a student of Class XII, I did this project as a part of my Studies entitled I owe a deep sense of whose valuable Gratitude to my biology teacher. advice, guidance helped me in doing this project from conception to completion. At the same time, I cannot forget to express my for gratitude to our school Principal extending support patronage and constant encouragement. Finally I am thankful to my parents for helping me economically, and my friends for being a helping hand at every step of this project INTRODUCTION DNA fingerprinting is a laboratory technique used to determine the probable identity of a person based on the nucleotide sequences of certain regions of human DNA that are unique to individuals. DNA fingerprinting is used in a variety of situations, such as criminal investigations, other forensic purposes and paternity testing. In these situations, one aims to "match" two DNA fingerprints with one another, such as a DNA sample from a known person and one from an unknown person. There are various methods for analyzing DNA to establish if two samples are the same or different. This is sometimes referred to as DNA fingerprinting. For example, two cloned pieces of DNA can be studied in the laboratory to determine if they have portions in common, and thus overlap with one another. DNA Fingerprinting In different setting, such as a crime scene, DNA samples can be collected and analyzed to determine if they match DNA samples obtained from suspects of that crime. If two DNA samples have the same fingerprint, then there is a very high statistical likelihood that they came from the same person. Such an approach can also be used to establish paternity. satellite DNA ATOCTATTOO minisatellite microsatellite RRCKKKKCANCACACACACACACA microsatellite Historical Background In the course of his research on variability in human DNA, Alec Jeffreys developed a method of forensic DNA typing. This method, termed 'DNA Fingerprinting', was used for the first time to solve two rape/murder cases in the UK in 1987. Jeffreys was knighted in 1994 for Services to Science, and has been the recipient of numerous other honors Sir Father of DNA fingerprinting in India Born in Jaunpur district of Uttar Pradesh, trained in UK in DNA fingerprinting, Prof Lalji Singh, did groundbreaking work in Hyderabad, to etch his name in Science forever with his contributions. Pro Lalji Singh