Paediatric Drug Calculations | The University Of Western Ontario - Edubirdie

University:
The University Of Western Ontario
Course:
Biology 2290F | Scientific Method in Biology
Academic year:

2022
Views:

310

Pages:

3
Author:

Kyuwon J.

Paediatric Drug Calculations ● Paediatric drug calculation principles ○ typically weigh-based ○ Dose = mg/kg x weight (kg) ○ Volume to give = Dose/concentrations ● ALPS emphasizes ○ Accuracy ■ Target. Children tends to have narrower therapeutic windows ○ Weight estimation if real weight of patient unavailable ■ Broselow ■ Age-based formulas ○ Standardization ■ avoid calcu ■ lation errors ■ most often used in emergencies ○ Pre-calulated charts when possible ● paediatric weight Estimations ○ Actual weight is always preferred ○ Age-based weight Estimation ■ ALPS ■ ALPS is used to simplify approximation ● used to speed up dosing decision in case of emergencies ○ Broselow Tape ■ Standard when weight is unknown ■ Color zone = pre-calculated drug dose Emergency Drug Calculations Cardiopulmonary Arrest Drugs ● Epinephrine (1:10,000 IV/IO) ○ Dose = 0.01 mg/kg ○ Volume = 0.1 mL/kg ○ Frequency Every 3-5 minutes ■ ex) 20kg child ⇒ 0.01 x 20 =0.2 mg (mL) should be given ● Aminodarone ○ Shock-refractory VF/pVT ○ 5mg/kg ○ may repeat to make total of 15mg/kg ■ ex) 15kg => 5 x 15 =75mg ● Adenosine (PSVT) ○ 1st dose ■ 0.1mg/kg ○ 2nd dose ■ 0.2mg/kg ○ ex) 25kg ⇒ ■ first = 2.5mg ■ second = 5mg ALPS emphasis avoidance ● Decimal misplacement ○ 0.1 vs 1mg/kg ○ Use of adult concentration without use of dilutions ○ Forgetting max dose limites ○ Wrong routes ■ IM vs IV ○ Incorrect weight estimations Medication Dilution Essentials ● Epinephrine 1:10000 = 0.1mg/ml ● Midazolam 5mg/ml ● Aminodarone 50mg/ml ● Ketamine 10mg/ml ○ 50mg/m; ● Dilution formal ○ C1V2= C2V2

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