Types of Debridements - Edubirdie

University:
The University Of Western Ontario
Course:
Biology 2290F | Scientific Method in Biology
Academic year:

2022
Views:

475

Pages:

3
Author:

Kyuwon J.

Debridements ● Used to remove unhealthy dead infection or contaminated tissue ● clean wound bed ○ healthy tissue can regrow in that location ○ healing Types of Debridements ● Surgical debridements ○ through surgeon or specialist with scalpels, scissors ○ most precise method ○ used for severe infection with larger wounds ● Mechanical debridements ○ physical removal of tissue ■ we-to-dry dressing ■ irrigation ■ wound scrubbing ○ effective but painful for patients ● Autolytic Debridments ○ using body’s own enzyme ■ Combination of enzymatic activity and moisture will break and dissolve dead tissues ● collagenases ○ breaks down denatured collagens ■ major protein in necrotic tissues + eschar ○ preserves healthy collagen on granulation tissues ○ Most effective on moist wound environments ● Papain-Urea ○ it could be combined and used with Chlorophyllin ○ papain ■ proteolytic enzyme derived from papaya ○ Urea ■ used to denaturing proteins, ■ exposes sites for papain to be applied ○ Chlorophyllin ■ added for odor control ■ reduce inflammation ■ has concern on allergic reaction and availability, therefore, is rarely used in modern day ● Streptokinase-Streptodornase ○ streptokinase ■ activation of plasminogens =>plasmin (clot-dissolving) ○ Streptodornase ■ liquefies pus and DNA from dead cells ○ Used a lot on past but is replaced with safer alternatives ○ used commonly once if surgical option is not suitable ● Biological Debridements ○ Maggot therapy ○ sterile, lab-grown maggots are used to place inside the wound ○ eats away only dead tissues ■ leave healthy tissues intact ○ used rarely, but is effective on chronic wound therapy Usage ● Chronic wounds ○ diabetic foot ulcer ○ pressure sores ● Severe burns in dead tissues ● Traumatic injuries ○ often dirt and foreign matter inside the wound ● infected wound ○ usually does not respond to standard clinical cleaning

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