Week 14: Cellular Metabolism. Part 3 | The Pennsylvania State University

University:
The Pennsylvania State University
Course:
BIOL 230W | Cellular Biology
Academic year:

2023
Views:

471

Pages:

1
Author:

Sarah Landeck

BIOL 230W - Week 14 Cellular Metabolism pt 3 — Acetyl CoA is oxidized in the citric acid cycle via oxidative phosphorylation —> steps = hydrolysis into building blocks, conversion to Acetyl CoA, oxidation — Before entering cycle, pyruvate converted to acetyl CoA, makes CO2 + NADH —> oxidation of NADH and FADH makes most of the ATP in glucose catabolism — Oxidation generates ATP by transfer of protons and electrons — Protein complexes pump H+ to inner membrane of mitochondria from matrix — Electrons that escape the ETC form reactive oxygen complexes (apoptosis) Cellular Metabolism pt 4 — If a cell has high levels of G6P, there are also high levels of glucose —> High G6P inhibits hexokinase to allow glucose to be exported from the cell — Allosteric regulators bind to an enzyme at a site other than active site, change conformation and therefore the functions