Heart Failure With Preserved Ejection Fraction (HFpEF) - Edubirdie

University:
The University Of Western Ontario
Course:
Pathology 3500B | Human Pathology
Academic year:

2023
Views:

466

Pages:

3
Author:

Kyuwon J.

HFpEF ● Heart failure where ejection fraction is normal or preserved ○ ≥50% ● Diastolic dysfunction ○ Heart is unable to relax properly ○ Poor ventricular filling HFpEF vs HFrEF ● HFpEF ○ Normal EF = ≥50% ○ Filling problem ○ Diastolic dysfunction ○ Thick LV wall ○ HTN a common cause ● HFrEF ○ Reduced EF = <40% ○ Pumping problem ○ Systolic dysfunction ○ Thin or dilated LV wall ○ Commonly caused by MI Cause of HFpEF ● Hypertension ⇒ LV hypertrophy ● Aging ● Obesity ● Diabetes ● Coronary artery disease ● Atrial fibrillation ● Chronic kidney disease Pathophysiology ● Long-term hypertension ⇒ left ventricular hypertrophy ● Thick stiff ventricle ⇒ cannot relax ● Reduced filling ⇒ decrease in stroke volume ● Blood backs up ⇒ pulmonary congestion Pump is strong but filling is poor Cx - same smx as heart failure ● Smx ○ Shortness of breath ○ Orthopnea ○ Paroxysmal nocturnal dyspnea ○ Fatigue ○ Exercise intolerance ● Signs ○ Pulmonary crackles ○ Peripheral edema ○ Elevated JVP ○ S4 heart sound ■ Stiff ventricle Dx ● Echocardiogram ○ EF ≥50% ○ Diastolic dysfunction ○ LV hypertrophy ○ Left atrial enlargement ● Blood test ○ BNP elevated ● CXR ○ Pulmonary congestion Mx ● Control underlying conditions ● Tx ○ Control BP - critical ○ Diuretics ⇒ for fluid overload ○ Treat AF ○ Treat CAD ○ Lifestyle factor changes ■ Weight loss ■ Exercise ■ Salt restriction ● Medication ○ Diuretics ○ ACE inhibitors ○ ARBs ○ -blockers ○ SGLT2 inhibitors

Related Documents

Heart Failure With Preserved Ejection Fraction (HFpEF)

Heart Failure With Preserved Ejection Fraction (HFpEF) - Page 1

Heart Failure With Preserved Ejection Fraction (HFpEF) - Page 2

Heart Failure With Preserved Ejection Fraction (HFpEF) - Page 3

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