K-Complex | Lecture Note - Edubirdie

University:
The University Of Western Ontario
Course:
Pathology 3500B | Human Pathology
Academic year:

2023
Views:

410

Pages:

3
Author:

Kyuwon J.

K-Complex ● Sudden, high amplitude waveform ● Could be seen on EEG during non-REM sleep ○ Stage 2 -N2 ● Largest single waveform in normal human EEG sleep patterns ● Sharp negative deflection by positive wave ● High amplitude ● ≥0.5 seconds ● Isolated frequency - not rhythmic Structures of K-Complex 1. Sharp negative waves - downwards deflection 2. Following slower positive waves Biphasic patterns will make it easy to identify in EEG K-Complex Occasions ● Spontaneously ○ Occurs naturally during Stage 2 sleep ● Response to Stimuli ○ Triggers ■ Sounds ■ Touch ■ External disturbances ○ Evoked K-complex Function ● Sleep Protection ○ Suppression on cortical arousal ○ Prevention of waking in response to minor stimuli ○ Small noise ⇒ K-complex ⇒ not wake still sleeping ● Sensory Processing During Seep ○ Brain is still monitoring environment ○ Decides which stimulus is important ○ Used as filter system during sleep Feature K-Complex Sleep Spindle Shape Single large wave Burst of oscillations Function Protection Memory consolidation Timing Often precedes spindle Follows K-complex Neural Mechanism ● Made my thalamo-cortical circuits ○ Involvement of cortex and thalamus ● Interaction between sensory input + cortical inhibitions Cx ● Seen in healthy sleep ● Stage 2 of NREM ● Abnormalities: ○ When reduced K-complex, represents to sleep disorders ○ Absence may mean brain dysfunction ○ Altered pattern is seen in aging or mean neurological disease Memory and Learning ● Memory consolidation ● Synaptic plasticity ● Works with sleep spindles and slow-wave activity K-Complex vs Other EEG Waves Wave Stage Function Delta Deep sleep Restoration Theta Light sleep Transition K-complex Stage 2 Sleep protection Spindles Stage 2 Memory Beta Awake Alertness

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