Osteoarthritis Pathophysiology - Edubirdie

University:
The University Of Western Ontario
Course:
Pathology 3500B | Human Pathology
Academic year:

2023
Views:

65

Pages:

3
Author:

Kyuwon J.

OA ● Degenerative joint disease ○ Breakdown of cartilage in joint ● S/smx ○ Pain ○ Stiffness ○ Reduced joint function ● OA common form of arthritis for older adults Pathophysiology 1. Articular cartilage gradually wears down 2. Protective cushinging between decrease in bones 3. Bone rubbing against each other 4. Inflammation/pain/joint damage 5. Bone spurs may develop around or near joint Affected joints (commonly) ● OA oftenly affects weight-bearing joints ○ Knees ○ Hips ○ Spinal cord ○ Hands ■ Joints in finger R ● ● ● ● ● Increase in age Obesity Hx of joint Repetitive joint use FHx Cx ● Joint pain worsens with activity ● Joint stiffness ○ After rest ● Reduced range of motion ● Joint crepitus ○ Sensation of grating Smx worsen over time Complications ● Osteoarthritis will lead to various complications ○ Joint deformity ○ Reduction in mobility ○ Chronic pain ○ Disability Dx ● Medical history on physical examination ● X-ray ⇒ show joint space narrowing + bone spurs ● MRI in some cases Tx ● Modification in lifestyle ○ Weight reduction ○ Regular exercise ○ Physical therapy ● Medication ○ Acetaminophen ○ Ibuprofen ● Surgical option ○ In severe case, joint replacement surgery is an option ■ Knees, hip replacement

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