University:
York University
Course:
SC/BIOL 3120 | Immunobiology
Academic year:

2023
Views:

174

Pages:

3
Author:

Niklas

Hypersensitivity Introduction Basic Model for Immunity Entrance into body (Antigen) (Pathogen) Recognition Effector Response what if the response is worse than the antigen? Hypersensitivity Allergy Hypersensitivity Reactions: inappropriate secondary responses against relatively harmless antigens - as a result, these immune reactions result in more harm than benefit --> The worse than the antigen Hypersensitivity Types are classified by: 1) time until response (seconds to days) 2) mechanism (cells/molecules responsible) 3) types of damage caused Type I Hypersensitivity what constitutes an allergen allergen: substances that elicit an allergic response - usually small glycoproteins that contain multiple epitopes - usually have: - internal enzymatic activity - may contain PAMP or PAMP-like structures - enter the host through mucosal tissues at very small concentrations Allergy: the tendency to develop a heightened immune response against something normally considered harmless Examples: Hay Fever, Asthma, Eczema, Food Allergies