University:
York University
Course:
SC/BIOL 3120 | Immunobiology
Academic year:

2023
Views:

413

Pages:

2
Author:

Niklas

Consequences of the Memory Response Original Antigenic Sin Large-scale public health measures for infectious diseases: - Why are different people responding differently? - Based on our MHC proteins, we may be able to recognize and respond to antigens differently. Consequences of the Memory Response Original antigenic sin: 1) how we are originally imprinted based on first exposure/previous experiences 2) class reactivity 18 Active vs Passive Immunity Active Immunity: antibodies are naturally made by the body Passive Immunity: antibodies are pre-formed and donated Natural Immunity: part of nature Artificial/Acquired Immunity: not natural, manipulated How does passive immunity happen? Antibodies are taken from another source, purified, and then administered When would you use passive immunity? - an individual with an immune deficiency - especially deficits in B-cells/antibody production - toxin/venom with an immediate threat to life - usually considered therapeutic (used afterwards) When should you NOT use passive immunity? - it doesn't activate the immune system - not as effective as a vaccine - anti-isotypic antibodies could cause problems - recognized as foreign, causing an unwanted immune response - if the need is prophylactic (needed before)