University:
Swansea University
Course:
PM-133 | Evolutionary and Molecular Genetics
Academic year:

2023
Views:

241

Pages:

2
Author:

Amal J.

3 Models for Promoter EscapeoInchw armO crucchioTransientmodelexcursion2 domainPol stay inconnect withone Placed &RNA pol detachedfor a short time andflexible linkerbegin to synthenterabort fivelextendandRNA, DNA FoopPolymerase andout,and thetranscriptiondetach,after tenloopoutcreateNT first domainan energy topull the secondescope RNIAdomainendpolfram promotecouponscontinue with-blondation.34 2 types fectiting by RNAPolI. Pycophospory Citic ecliting - incorrections2. Hydroly tic editingcheckingleave as ARNTDholffor removing errorencorreal nuclectidilave as RIV IN P.but to keepin pacewith translation"when RNA pol exceeded apin ocorrect nucleofidelifer binding of ribosomes and keep upthe paceRNA pol backtrack 2-3 NT's, Gre A protein assist living)the cleavage if back track in more (0.18NTS)are Bassitts inediting '(3'. s'proofreaders1 when on in correct2. when on innucleofide enter thousingnucleotide polymeusenucleofide hydrolysetoThey back track 2-3nucleofidesianNMN+PPi enzyorecleave 2-3noclectidesrecognize before handwith the helperformation withgrowingGre-A (RNAPSTingOH,' NMN7PPI- Rejointhe 3'-5' nuclease),Gre-B 18NTS.to NTP and lear refromactivesite.TRCETranscribed for encounter a lesion, they stabll andcreatess a blast, TRCF comes collides with thepol and push HB polymerase tocostinue synthesisand recurte proteins for repairTRCF - Transcription Repair Coupled factor.