University:
Swansea University
Course:
PM-133 | Evolutionary and Molecular Genetics
Academic year:

2023
Views:

191

Pages:

3
Author:

Amal J.

-Upsteram BindingfactorJollTfform 2toms (roll2times).Interact with corepromotercomplexTFrecruite SL-13-humansTBP+TAFTIF-1B - micecomplex(5 TAPS )Interact to corePpromoterTIF-1ARNA Pol Ibegin transcription.transcript producedTerminateonly inPform they recurte RNAPOl I, so it in ataigentof regulationTarget of RapamyanP.when nutrien availableTOR(active)TIF-1AkinaseTranscription Termination FairtTermination (2proteins)(TTF)Polymerase TranscriptionTTFRelease factor (PTRF)hundstoRNA pol stuck (stabl.SAL boxwhen they meetPTRF comes and(TerminationSAL box with TTFremoves pol If TTFsequence) Jonal (C/D)(c/p)Transcript RUGAUGAProtected (a/d) region18'sETS.5.8S285 CUGAPRITS. IPRETS.TS-2ExternaltranscibedInternaltranscribedspacerprocess spacersspacas removedby processing enzymesU3 spliciosome is involvedin the processingProtected from nuclease actionProtected region (2modification)a DFCMethylationPscodouridylationSugaregicytorine methyBase attachedcylorineto 5th carbonon Nitrogenous2small RNAin nucleolesbase in psecolorideinfluence these 2 processshoRNAsmall nucleolar RNA [marking of protected regions] 2 SDORNAtwo box cto)Pairwith RNA and mark sitefor methylation(CCRUGAUGACUGABox H/ACA18S5.8528S.Boxcmask siteMethylationBoxD.for 40Crihosome are transcrited.,AN ANNA ACAevenly in M-phase,inhigh requirementBOXHBOXACAAfter1855.85285processingMove toGCX-mastrec@GC combine with proteins (schoomal proleinlike5'gone transcribedhytermRNA pol II, translated5'1in cytoplasm andStat3'3'transported to GC)Several RNA-rihosomal genes are ExamplePol engagedinof actively transcribed geneseach transcriptionalunit w atimethey show a X-mas tree likeappearance :