University:
Swansea University
Course:
PM-133 | Evolutionary and Molecular Genetics
Academic year:

2023
Views:

309

Pages:

3
Author:

Amal J.

Slowblock (cortical granule reaction- 15,000 cortical granules in peripberal cytoplasm,when spein binds itactivate and on enzymephospholipasie IIC4NADPH pglutathione(Protectiveseaventyreductaitspaim + Egg PMoxyracticalsGPCR&Peotectegg DNAfromexocytosisdamagCGSPTyrosine activate PhorpholipasekinaseMPSactivatedC presentin the inner sideof Planma MembUdX1(PLC)PLCYHyalineCleavagePIP2PreventionDAGPhosphatidyl FrositolIP3Institoldiacylof polyspency4-5 BerphosphateTriphosphateglyceidElevated Co responceexIMAP to Ca2+ Resume cellaycleNat, HtCa2+2NAD NADKings NADP+membronechannelJ. influx exchangesbiogenesis.alkaline activationNADP+openerP.3 gated Ca 2chabelcytoplasmRNAmembNAADPCa21biogenesisER ca2+efflueca2releasedCortical syo. tromplation(blastulation)furtherinto cytosol.ca2texocytosis3CalciumNADPH+O2requestescertical granclereactionH2O2organCleavage/crosslink (YE-OFF)Celldivision.Egg activation V.E (vitelline Envelope) CorticalCortical granulegeanuleserine proteanecertical glanule content releasis anenzymeisPMcorticalgianalthecleaved by CGSPCGGSPProtein postspaceblwPM&V.E.cleavageandclippingBocyteCGSPclip off bindin recepters.of bindinreceptor.MPSnofertherMucopolysaccbaridereleased fromspermcanbindcortical gianoles create an esmotic gradientin the space.MPSabsor hs water into space b/w VE &PM. andthe gap increases.UdxI proteinIt produce hydrogen peloxide H2O2which in the substrate for properoxidase & Tronsglutamibasewben gan increase theres a chance for breakageof.PM&V.EThese strenglpens the V.E formingotherfertilization envelope C by ciosslinking proteins in V.E]ngerV.EF.E(orovopeoridax&trons glotambrace.RNAreplationrelation)Hyaline - Cortical granule proteins, which covers PMthroughout and provides strength to blastot blastomereduring cleavage [fight hyaline layer] marvillafromPM joins with Hyalineovom me productionPolyspamy Prevention in Sea urchincontridefromfather2methodsthe2Slow block1Fast Blockcortical granutyreaction.transient(2-3sec)Permanentmillresting membrone potential- 70mVApt membrone potentialwhere sperm cancasilybind.First sperm bindsNatIncreased influx of pattrooium ions into theoocyte cytoplasm.+ve change of sodium creates anelevated membrane potential of 20mV, this inveryfast rise (in one second) and fortha sperm cant bind athigher membrone potential, after sometime the membcan regain it's originalpotential ( in 3 sec) so there inachance for polyspermy, so called polyspermyIn case of pond ecosystem, CT efflux outs and witnescreates the +ve memb potential.1150)soights776 ay blairroom