University:
Swansea University
Course:
PM-133 | Evolutionary and Molecular Genetics
Academic year:

2023
Views:

195

Pages:

4
Author:

Amal J.

Drosophila MelanogasterThomas Hunt MorganD.M prolific, least no: of etromorone, easy to colturemotonts -reveal - genetic aspectsmost of case eggactivation happens after feitilizationbut in DM D.m if happens beforeDeringovolationEgg basto squeeze through narroworidoctopens cantchannels in Egg PMCa. Enter socyte cytoplasmoooyte nucleus resumesmelosis IInurse cells produce mRNA during movement throughoviduct and accumilates in oogonia cytoplamGeimalium.micropylasopeningfacilitatespermentry.oocytenorsecell Prevention of polyspermyTail of spain 300 times longa than bumonspain. The tail in present in the micropyle preventingentry of second sperm.During speim entry egg in undergoingaxcis specification.first specified anterior posterior ascis.NOnurseculsfollicle cells - maternallydelivedoocyte(nurse cells producefutureGurken mRNA - -greatlyingposterioraffectionwighoocytenoidsideTransported to oocyle throughnucleus seenring canal.closer towardsfollicle cellmoves to the "ocyte nucleusenddue to affectionTranslated to Gorked proterollston indiceat the viscinity of egg. Gorken protein receptons are present in follicle.cells.Torpedo receptorGurken bind to terpedo receptor in terminal folliclecells.Theyare converted into posterior follicle cellsnowcells produce some moleculesUNKOWOODunknownPKAStaufen, OSKARactivate Protein kinase APar1PKAin oocyte cytoplasmLfBtubolins.FuturePerleuorside)(activate cytoskeletal molecules)recruite Pas 1(partition proteins)NATIONAL cmicrotobolas && Btubulinseuispaymentation staibformmicrothote of sub future posteriorregionpolymerizationPolymerization startsdistant assirus of bststerorTPolarity@ Postaionto I toother anterior Stufen protein- - from nurse cellsTransported to oocyteoskar, staidenvasa determinantsOskar mRNA -from nurse cels.ofgermplasin00reach posteriorTranslatedhelps in localizing OSKAR @ posterior side.proteinrequitemorePas 1 protein Crecroite xf Btobolins)helps instabilizingmicrotobole organizationmotorproteinsdyenin- -ve end directed motor proteinkinesin + end directed3'UTR of MRNA bind to motor protein & help themreach destination0101OSKAR binds kingsin& move towards tend&poles plasmposterior region having distinctcytoplism due to presence of deferming