University:
Swansea University
Course:
PM-133 | Evolutionary and Molecular Genetics
Academic year:

2023
Views:

176

Pages:

4
Author:

Amal J.

Complex - I46 polypelides, Margor complex:NADH2FMNfirst e acceptshapedaim has FMNProteuditomatrix (verticulaim)FMNH2lie inmentrone (horiginal aim)Sereis ofFes(passing the electrons)ioron- solfer cluster3tunedor Fes2Fe2SIICysCysCysCysI(Fe2 Fe2SCysCysCys.CysFccordinatewithcysteinefe participate in iron e- transfer, proteins helpthemin the process : Fecordinate with proteins in the complex4Fe4show H+ Jumps when e - arrivesSysCyse-Ht4fe 4SJumpsH+CysCyse-Complex II [unable to pomp H+]4 polypetides, smallestTCAcyclenzyme locates in mt matrixexcept succinate dehydcogenaneis a part of complex IIFe-Sclosters.FA (hydeophobic)(hydcophilic)UG0UhiquinonH3COCH34.2 (e-e-when they acceptUOUQUQH2Semiquinoneubiquinoneuhiquinol2e, they accept2Htforom matrixand moves throughmembrone andComplex III - Cyt bC1deliver itto 2e-to C-III (intermenb11 polypeptidespace)(I) UQH22e to fes& Ht to intermembracytb&CytC1space1e1e-CybCJ (singlebalCysHisFeReiskeicacceptor)bhCusHis centreUQ(II) UQH22e to fesQcycling.UO1e-OH1e-UQUQQH2TTbLIIUQH2bLsenICyboUQH2fes HC1bHle-IIIUQUQH2intially all organisms helecotrophiclater CO2 increasedethlorophylevolvedIf CytC1de acceptoroxygenChancetoproduceoxydradicalnotDamageoxyradicabacteriaDNAused theproteinkillingif e skipetcOxygender a- Complex WCUA 2CuA present.CIVcyt A+ 2coppelcytA3ionsCuBCyt AA complexO2 + 4e+4++2H2O.Cytc le-CoA/WAle-cyteCytAO2cytele2H2OCytA3le-CytcCuB2NADH240Qcytc4e&4H+ae-Ooae-0021tL2HH2OH2O