University:
Swansea University
Course:
PM-133 | Evolutionary and Molecular Genetics
Academic year:

2023
Views:

215

Pages:

3
Author:

Amal J.

In awaerobic conaltion - actively contracting musclefast twitching musclebuge amtof glycogeIn muscle.abaerobicslow twitching - aerobiccancercoocoo-cellslactateC=Odebydiogema H - C-DHINADH,H+CH3CH3NAD+PysuvateLactatemuscleblooddead end productliverlactatePeacuteGlucosegluconiogenesis.To regenerateNADH (eventhaO2 isahrequired byglycolysis.In yeastglucosepreffered sourceanaerobicethanolTCAHAlcoidcoodebutioPyruvate DecarboxylaseHICFORgemaneCH2OHC=OIbondbreak NADII IICH3CH3CH3CO2NAD+EthanolAcetaldePyrovatehyde.PyrovateLink b/wAcety I CoA GlucoseATPHexokinaseGGPADPGlucose -6 -PJsomeraseFructose 6-1 PATPPhespho fructo kinaseof ATP, citrateADPFructose 1,6 bisPAldoseDHAP"Glycardehyde 3 PTriose 2NAD+Glyceraldehyde3-PPhosphate NADHKdehydegonaseJsomerase21,3 Bis Phospho Glycerate2 ADP3phosphoglycerate kinase2 ATP K2x 3phespboglycerate110Mutase2X 2phosphoglycerateEnolaseH2O2 X PhosphoEnol Pysuvate2ADPPyruvate kinasehigh ATP.2ATP.2 X Pyrovatesit Lightreactionit's -P-QH12H2OCO2 +12NADPH, H+dHPhotosynthesislightNaDHDark reactionNADH12NADPH +6CO2CHH12O6 (Glocose)D fromglocoseGPOHcleavage 12C of 1 4C but fructor23Cit ofSubstrate level phosphorylation - 4ATP(ATP 1.3kcal/mol)HO4C1regulatoryslep C =0CH2OHCIrreversible2H--OH1H-C - - 011 PhosphoC=O(32kcal)cluroHO-C-HhexokiniseIsomelase011-C-ItOH-C-HH-C.-OHATP-7.3kcalHC-OHH C - OHH-OHGlucoseAPP3.2kcalE Operation H - C - OHHC-OH-7.3kcal C H2OHin coupled-4.1kcalwith ATPCH2- O-PO3-conversionC H2 - PO22GlucotisetobalanceGlucose 6- PFructose G.P.all sonstrate levelATenergyATPPhospboPenzyme consider productCommitedtruclokinaseCH2 OPO32-DPnamestep.II irreversible3HC=04DHAPCH2OPO32&CH2OHC=OTIM2-+la> H - C-HH3P0Oremove and add PiAldose+ SbreakC52molewlesHLCHOOH - C=OHG3P4H - C-OHIH - C -OHH - C - -OHCH2OPO,2- RNADI12NADH,H+CH2OPO32-CH2O# FO32+2 1,3,his P2Pi2G3Pfruc 1,6 bin Pglycerate2ADP6I sobstrate liveP3 PGKinaseIII irreversible2ATP2x-92x coo40071CC=O8enolaxPK2xmolaseC=OPO32-H - C-OHFItD-C-0-P03112ADP2H2OCH2CH5H.-nm2-CH,OH)2ATP+QHPersont