University:
Swansea University
Course:
PM-133 | Evolutionary and Molecular Genetics
Academic year:

2023
Views:

86

Pages:

3
Author:

Amal J.

Oxidative Phosphorylation- Flow of NADH, H+ creates an H+ gradient ,used togenerate ATP- mt evolved from bacteriaouter membr one permeable to mostcompoundsThrough VDAC - Voltage Dependent Anion Channelmyelin sheathInnementrone- 75 1lipit- 80% protein large no: of invaginations- heartand liver moreboundary membrone - special cardeolitin lipidCadiacentocristaeoutamentrone)for accomidation(matrix)H+H+ cataly tic domainof these complexesATPIn intermembra common bacteiiumBacteria anscestor of mt & chloroplast(billionevolved firstyear lateBactelia58singleme6Ovesideformed from synthasecarging legionThis fosed to forminner men530mt evolveagain vesicld80- -vesiclevesicle formthylakoildofchloroplast evolvethylakoidH+ with synthaseacceptingdomain face Hyylakoidlomen. mohitlecavier b/w1,24(3e-e-UQC-3C-1eie-O2C-2C-4NADH2Cybe e2H2OdonateH+FADH2 donate Glonate e-hotcannotHt pumpHtUQ- - highly hydeophobic1.23mobile carliaReason for evolutionof ComplexesCytchighly hydrophilic34energy presentinglucose 613 kcal(ONaDH2C1pump 4H+almost2FADH290%C2unable to pump HtNADH24+4+2energyCzpump 4HtIATP IIATP III//2generateG of NADH252.6ATPF4pump 2H+Heat2.5ATP/dessipaticTATP duringclureNADH2convenionFinal acceptor of% sation offlowgenerate,gradient of Ht ande in O2.NADH2 2.5this 11+ flow back to% ratio ofmatrix, rotate aFADH21.5motal and generateAP2reductants