Amphibian Oocyte Maturation

University:
Swansea University
Course:
PM-133 | Evolutionary and Molecular Genetics
Academic year:

2023
Views:

64

Pages:

2
Author:

Amal J.

(DAmpbibian oocyte materation (frog).Raba pipens3yrs for oogonesisDuring last 2year. oocyte matures and storelarge amount of proteins and become large, oocyte isabsfilled withyolkFormation or r filling of Yolk- Vitellog enesistransfered to oocyte cytoplamYolk materialIn amphionsoocyte in assestedVitellogen in - Yolk proteinI 70 K Dafor several years until the frogattains sexual maturityDidyalfingolage.moleculeproduced in livelI asseste @ diplotene stage of Meiosis Itransported throughbloodstream andMaturation Promoting factor (MPF)reach oocyte cytoplamin not active till it attainsmicrispromoting factors.sexual maturityMPFCyclinCDKeg: P34. After it attains sexual materityactive (8)Progestronelactivates MPFmanCalmodulinCalpainCMOS (kinase)dependentII CPedanProtein(cleav).APCmechownkinase IIInhibitP2P3HMelphaseCMOSactivateCyclin B- CDK2InhibitMapkAPCInactiveCdk2 (mphaseinactivateMpfactiveCDK).DiploteneAPC freearrest removedAPC CohosinProgressof Gubiaritinof1cellcycle(same block in humansMeiosisgoAlso)stages are similarCMOS2ndest @ metaphase II ofProtein+meiosis (duetocytostatic factor (SF] tCdkzactivcomplex.ate+PinhibitThese arrest in removedprogressionMapk2of MIIMEK)(mitogen+Phosby speim entryphoactivatingErpIrykProtein kinase)Petime of fertilizationK actty 3.kinonInhibitLMap 3, Map2, Map.(Raj) ( MEK) (erk)gritascalcium influx @ eggcytoplasm1Anaphase PromotiComplexCalcium binds to Calmodolinenauting E3 bellow Marks BBYigase Cantondeigoactivatedwas dhaphase8R thromosomal alls seven Flhydeaving cohesin2311000 ota) bases parripoon