Oogenesis in Drosophila

University:
Swansea University
Course:
PM-133 | Evolutionary and Molecular Genetics
Academic year:

2023
Views:

99

Pages:

3
Author:

Amal J.

oogenenis in DrosophillaModel organism in DB.Meridistic oogenesisbcs duringthe tym of orgenesis, the oocyte oogonia. in in contact withpourishment to developing overyte through agtoplanicneighborring cells, the neighbouring cells provideconnection.oogoniaJosomecytocyst (aldready determines whichcell forms oocyte)cytoplasmicconnection (ring canal) Protein sichmolecute4Fusome Cepectrin rich)&which spons the ring8canal Fusomecells which get major16cellstageamount of susome becoithe oocyte@ 16 cell stage 2 cells in the (6 cells has (4) ^ aftoplasmicconnectionthese 2 cell acquire max nutrientsentirefrom neighbouring cells!16 cells areThey equal fate become rocytecovered in a chamber ofegg shell called germauiumonly jone becomes of Spencymusla&1oocytepotent cellsoocytes15that becomesnurse cellsProdixemniva transported through 2 stails ring meisis canal but into only oodytes. I completesoocyte MammalsPGC not able to differentiate by itselfgonads determiof or or gametes.gonads give licencing factors which helps in differeinto Qt or orDAZLProtein in developing gonad that act asliscensing factor For male and female sex detin]Writi(Meiosis initiated by 2 molecules(allRetinoicinfemales meiosis staits atacidgoetos stage (5months]In males meiosis startsBlocked @ diplotene I@ pobertyIn female PGStra 8e gestationproteinUpregulated by Retixacidbecomesfemale.Progression of meiosis@ gestation.upto 13dayIn maleofermininhibit Stra8Retinoic acid degraded by Cyp 26 one (gestNapos 2 absorbibit Stras (Nanosfirs idfwag bycome made BGameteDrosophila)RA(with statugnsibits meiosisFgf9Cyp 26CersistratistSoutherlyStra 8Nanos 2After 13gestationday of embry when we experimentally induce Nanos2 in femalegam cellsstra8 inhibitedMale fate.In male sertolicells are able to produce RetinoicacidQ pubetryStra8Progressionalmeiosis.