Spermatogenesis Study Guides

University:
Swansea University
Course:
PM-133 | Evolutionary and Molecular Genetics
Academic year:

2023
Views:

70

Pages:

3
Author:

Amal J.

spermatogenesis (65 days) (mouse 34day)Peoliferative phasePGCnumber increasethrough mitoois.3phasesMeiolic phasereduction(sparhatogonialdivisioncells)spermiogenesisformationPGCof spermatozoafunctional or sperm.gonadsIntegrated withsex cordsdiff esentiate into seminiferous tobules.from mature spains flushed to epideyclinesPGQbysemineferousroard +versides through epidy dimoespalipha2PGCSex cordswhen spermatocyles arrive tight junctionbetween sertoli cells at they squeese throughGonocytesand getinto lumon.mitosisPopulation of cellType AS spelmatogonia (mitoticallyProliferating)extencells)Integrate with satidicells (nourishment, kill spens&with incompletedins2890Leidingcells Intestitialcells$1000/18 withEproduce testosterone) SIseminefeiocs tobulesintesticial / Leidig cells produce testosteronetotas speimalogonialcell1000 speins -As typeBApool of typesType Ascellostemcells(2n)spermatogenesismitapticallycan any be of intiatedhord these(2n)millions of spermsType A1 spermatogoniala day(robertgtoplasmic connection( syochronised dv/pmnt of spermatogonia,fast nutrient transport)(2n)(25)A27) errorseType A2 spemalogonia A3 AC2Dpublic ON spermatogoriaType Bspamatogonia (2n) (Actoal phase from which meiosisstarts)Luxcild mutation in missiste ptelileduring spelmalogenesisthepool of stem cellscannotbe maintained and testisenergeAlbamesall be lacking sperm IIType B spermatogonia ( 2n)mitorsthemelons I (reduction)division.10 spermatocytes (still cells are cytoplasmic cally connected)small(trapled) 2n)meions Idown cooldspermatocyte (n) cytoplasmic connection helps in transferingnutrients from xetromosome causing cells toyethordTransition from spermatogoniacayingspematocilecells2 FactorsGDNF (Glial Cell lined Delived Neurotropic Factor)2 SCF Cstem cellfactor)Secreted by seitoli cells include follicle stimulating Hormone (FSA)GONF level 1 speematogonialmeiosisspermatocytehypitataryGDNFlevelmaintain stemcell poolSCFtransition of spermatorgonia