Introduction This essay will seek to discuss the role of androgen receptor therapy in advanced prostate cancer. Prostate cancer and the androgen receptor (AR) will be discussed, namely the origins of androgen receptor targeted therapy, its development and role in treatment of advanced prostate cancer today, and the future of targeted therapy. Androgen receptor targeted therapy is utilised in advanced prostate cancer to improve morbidity and mortality. The role of AR targeted therapies have evolved over the past 80 years...
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Humanism and Modernism are two completely different stances that American writers have used within their writings. Humanism is a democratic and ethical life stance that affirms that all human beings have the right and responsibility to give meaning and shape to their own lives. This ultimately means that humanism embodies that fact of building a more human society through a set of ethics based on human values in a spirit of reason and free inquiry through human capabilities. Humanism does...
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ABSTRACT In recent years, science fiction has become a favorite spotlight among other genres, from Tony Stark’s Iron Man suit to hi-tech world of Wakanda. In fact, science fiction has been a fellow of human evolution since the primitive of the science and technology era. By analyzing in depth the typical sub-genres with examples and comparisons between sci-fi creations, this research paper aims to point out the actual influences of science fiction to the human society and technology evolvement in...
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Syrian refugee women are more likely to experience mental illness due to various obstacles and barriers. Some of these barriers are from past physical and mental trauma, feelings of isolation from lost family support, language and culture difficulties, and the social stigma associated with mental illness. Imagine you’re a pregnant, female Syrian refugee, being forced to relocate from the war-torn country in which you were born and raised. Leaving all your family and friends behind or experiencing the horrific death...
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What exactly makes someone a “hero” or a “tragic hero” if you will? Aristotle defined a tragic hero as a man of noble birth with heroic qualities whose fortunes change due to a tragic flaw or mistake that ultimately brings the hero’s downfall. Their tragic flaws makes them more relatable or/and get pity from the audience. However a hero is understood to be different to everyone. Anyone who influences anyone else by saving or even helping save his or her...
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Early impressions Setting The film is set in the 1990’s in Pittsburgh Pennsylvania. The setting is established through Charlie reading aloud his letters. The setting of the film is integral to the storyline as it helps to establish one of the films major conflicts. During the 1990’s homosexuality was not as accepted by society as it is today. This is why Brad struggles with his feelings and somewhat hates himself for his sexuality. He hides his true feelings from his...
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Introduction: The Concept of Individualism in Dystopian Worlds Individualism is defined as “a social theory favoring freedom of action for individuals over collective or state control” (Google). There are two major forms of individualism that are prevalent throughout writings. The first form is individual vs. society, and it occurs when the individual must change his or her ideals in order to fight their government. The second is individual vs. self, which is an internal fight between good and evil. In...
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INTRODUCTION Numerous discussions over euthanasia have been going since ages among wellbeing experts. Euthanasia word originates from Greek and also widely known as willful extermination which means great passing or makes a finish of life effortless, shorting life in remarkable condition. Person's perspective toward euthanasia is relied upon numerous conditions, for example, religious background, race, and so on. Euthanasia can be delegated active and passive. Active methods acquainting something with cause demise and passive methods retaining treatment or strong measures...
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Throughout the novel, “The Meditations on First Philosophy” by Rene Descartes goes through a spitital journey of discovering what he believes to be his conception of the mind. The reader is able to see this through all of his meditations and the exploration he takes himself on to reach his final conclusion of the mind and body in meditation six. Each meditation that DescartesN writes touches somewhat on his conception of the mind and his beliefs that follow. In order...
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Pierre Balmain inadvertently created a national icon when he designed a kebaya in batik print to accompany a snug wrap skirt meant to be the sarong. The sartorial splendour of the sarong kebaya uniform, further accentuated by its hourglass shape and three-quarter sleeves, was an instant hit with the public, thanks to its femininity and fulfilment for the previous lack of ‘national identity’. My paper will explore the discursive construction of the Singapore girl in the light of a changing...
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Beowulf shows many examples of generosity, hospitality, envy, revenge, and loyalty. Although a righteous leader, Beowulf is riddled with flaws and stuck in his ways. The loyalty Beowulf shows throughout the poem is unmatched by any other. Loyalty is a great part of Beowulf because it proves that he can be a great leader. Beowulf expresses his virtue through being a leader and having loyal followers behind him. Becoming a leader as great as Beowulf, everyone needs to follow in...
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Roy has investigated the inconveniences of divorced and widows in The God of Small Things. The destiny of divorced women also is brought to the fore in The God of Small Things. Comrade Pillai's way to express the word as 'Di- divorced, presents mortality to Rahel. Divorced Margaret is close to a prostitute in Mammachi's eyes. Baby Kochamma's frame of mind towards isolated Ammu is typically Indian. Indian culture occasionally acknowledges widowhood sympathetically, however not a divorced woman. A widow...
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Sleep deprivation alters our brain chemistry, making us feel isolated and irritable. We know that by our own experience by finding it hard to stay focus, to communicate, and to stay positive throughout the day when we have to wake up early in the morning. Most people, nonetheless, do not appreciate and value sleep time due to not knowing that there will be consequences that follow for people who do not sleep enough hours a day. In other words, insufficient...
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The Hate U Give by Angie Thomas is a realistic fiction novel that provides a perspective on the two contrasting worlds of Starr Carter’s life: the poor, black neighborhood where she lives and the fancy suburban prep schools that she attends. She believes that she has these two worlds perfectly balanced, but that is proven false after Starr becomes the witness to the fatal shooting of her childhood best friend, Khalil, at the hands of a white police officer. Starr...
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The movie that plays in our minds when we think of the Civil Rights movement is one starring Martin Luther King Jr giving powerful speeches and inspiring both the Black and White populations to carry the banner for social freedom. Although Martin Luthger King Jr was a driving force in the movement, there were so many others who bore the weight of the cause who did not draw as much attention to themselves. There were countless groups dedicated to fighting...
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Introduction Stroke is a major public health problem globally and surviving patients have very high risks of recurrence (Wolfe et al, 2010). It is the third-largest cause of death in England(Raithatha et al, 2013). The World Health Organization defines stroke as “a rapidly developing clinical signs of focal (at times global) disturbance of cerebral function, lasting more than 24 hours or leading to death with no apparent cause other than that of vascular origin” (Coupland et al, 2017). However, the...
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Abstract This paper explores seven published articles that report on the psychological and sociological impact of Down syndrome for the individual and their family. Parents discuss the many familial effects of having a child born with Down syndrome. Most parents report having a child with Down syndrome as a positive experience while other parents report having a negative experience. Included in this paper are two studies, one conducted by Janet Carr of St George’s Hospital in London, UK, and the...
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In 1985, two large gas pipeline companies joined forces and created what we know as the Enron Corporation. The Enron Corporation provided commodities, utilities, and services in natural gas through its vast pipelines. Enron produced, carried and dispersed electricity through the northwestern parts of the U.S, among many other power associated ventures worldwide (Ferrel, Fraedrich, & Ferrel, 2011). During the 1990s, Ken Lay the Chair, Jeffrey Skilling the CEO and Andrew Fastow the CFO converted Enron into a $150 billion...
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Understanding Cultural Relativism: Definition and Origins The world is composed of many different groups of people who have unique perspectives on what they believe the proper way of thriving and surviving is. Each group and civilization has created their own unique culture and systems that have lead people to view life and lifestyle differently, and has raised the question of whether we can determine who’s ultimately right and wrong. According to Cultural Relativism, we can’t. Cultural relativism is an established...
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Human trafficking today is considered modern-day slavery. Victims of human trafficking are coerced, assaulted, and lied to have commercial sex. This year, I have noticed that human trafficking has become more prevalent in the media but I’ve also noticed that not much has been done about it. In Spears’ essay, she discusses how much human trafficking impacts the U.S. and states, “the current estimate is that 18,000 to 20,000 people are trafficked into the US annually” (Spears, 2006) but these...
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Shakespeare's literary works are notorious for being complex in nature and with many layers of meaning hidden within characters actions, motifs, and the nature of the genre. Reality, like Shakespeare’s works but on an elevated level, is likewise very complicated and difficult to understand, because of this, it is often looked to literature and film to relate ourselves to fictitious characters and themes in order to find order in the chaos of life. This same can be done when looking...
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Before Foucault, ethics was focused on the finding of oneself within a predetermined moral order or the creation of oneself in terms of a great transcendental ought. Thinkers like Bentham believe in an ethical theory rooted in an empiricist account of human nature. Bentham’s ethics reflects what he calls “the greatest happiness principle,” where he implies that ethics reflects the moral obligation to seek out what produces the greatest amount of happiness for the greatest number of people. This thinking...
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Imagine if a brain can primarily run on fatty foods such as bacon and cheese, well believe it or not a brain can most definitely only run on foods such as that nature. It may be hard to believe but the ketogenic diet is one of many diets that aren't well known by the average human. Due to the fact that few people know about it, they do not know of the benefits that come along with doing such a...
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Abstract Face recognition is one of the challenging problems which suffer from practical issues like pose, expression, and illumination changes, and/or aging. Plastic surgery is one among the issues that poses great difficulty in recognizing the faces. The literature has been reported with traditional features and classifiers for recognizing the faces after plastic surgery. In order to reduce the computational complexity of high-dimensional feature descriptor and improve the accuracy of recognition algorithm, the paper proposes Volume based SIFT (V-SIFT) for...
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Introduction Singer’s use of extreme hypotheticals to indicate how we should donate our unnecessary belongings, money, and time appeals to the emotional and logical sensibilities of the reader, but it creates a gray horizon because there is no direct explanation of what is considered a necessity, nor is there a law that states that one is obligated to donate. Despite Singer overshooting his argument, we should value the livelihood of the poor because prosperous nations have grown too accustomed to...
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Gender plays a key role for human’s everyday lives. The gender we are given to in birth can affect every aspect of our lives from personality to even the way we feel about ourselves individually. It can also affect the sort of hobbies and passion that we are interested in, to the way we dress and even socialise to even the sort of career path and opportunities we choose in life based on our biological features (genitalia). In this essay,...
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“It is a truth universally acknowledged that” ‘Pride and prejudice’ is the most influential romance novel of our time. Jane Austen opens literature to a whole new technique of writing and critique. A conventionally romantic novel usually focuses on the relationship between physically attractive man and woman. The hero and heroine usually meet early in the story and fall in love at first sight. The two lovers may, more often than not, have to overcome obstacles in order to be...
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Poetry has been around for centuries. Going back to the 2nd century. As poetry has been around for some time now. Poetry has a tendency of helping soothe the pain, suffering of mental illness and so much more. In “Will a poem a day keep the Doctor away?”, talks about the use of poetry and how today it continues to help people, especially women. So, I come to say that poetry is beneficial to helping people with mental health. Poetry...
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Subculture has the most ancient roots. In one of the Egyptian tombs, a papyrus was found 2,000 years ago, in which someone complained that young people began to wear strange clothes and sing other hymns. Subculture, therefore, is an ancient component of human society. The term “subculture” itself was introduced into sociology by the American sociologist David Reisman in 1950. Most often, the subculture come up from the common tastes and preferences. Fandom - fanaticism - in music, hobbies, sports....
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Introduction In this social media age, almost every entity depends on social media for marketing purposes. People buy and sell things on social media, get information about anything and also remain connected with distant relatives and friends through social media platforms. But there is one thing that makes me curious is – finding love through social media. There are many online dating apps as well sites which help people find someone according to their requirements. In earlier times, people used...
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