A disease is a specific abnormal condition that negatively affects the structure or function of part all an organism and there is different type of diseases including tuberculosis the most dangerous is the disease. This disease killed more people in the world, the research tells us about tuberculosis that who were killed form this disease.
The focus is the development of new drugs to treat TB because it has become resistant to drugs that has been used in the past. It kills more people in the world than any other infectious diseases Collaboration between scientists and other groups is very important to develop new and improved drugs/treatments for TB because it allows greater progress to be made.
Save your time!
We can take care of your essay
- Proper editing and formatting
- Free revision, title page, and bibliography
- Flexible prices and money-back guarantee
TB is an infectious disease caused by mycobacteria. It affects the lungs and it can cause death if not treated. Approximately one third of the world’s population is infected with TB. Unfortunately, TB bacteria have become resistant to the two most commonly used TB drugs, isoniazid and Mycobacterium avium.
Bacteria become resistant to antibiotics because some mutant bacteria have a natural resistance to the drugs. Bacteria breed very quickly. When treated with antibiotic the normal cells are killed but the mutant cells are not killed. Eventually the mutant cells replace the normal cells in the population. For example, drug resistance can be increased if people do not complete a full course of TB treatment, health care providers prescribe the wrong treatment (the wrong dose or length of time), and drugs for proper treatment are not an available and drugs of poor quality. (News, Drug-resistant tuberculosis reversed in lab, 2019 )
The scientific groups/ specialists connected all facets of Tuberculosis are; Infectious Diseases, pulmonary Medicine and research. The history of tuberculosis and treatment has been documented since 1944, these treatments have been discovered through trial and error.( past, present and future 2002 and 2019)
The Journal of Preventive Medicine and Hygiene Egyptian mummies, dating back to 2400 BC, reveal skeletal deformities typical of tuberculosis; characteristic Pott's lesions are reported and similar abnormalities are clearly illustrated in early Egyptian art. (OAIP 2017)
Tuberculosis has evolved thought history to defy rules of treatment. The data collected states that 558 000 people resistance to rifampicin (the most effective first-line drug) globally in 2017, of which 82% had Multidrug-resistant Tuberculosis (MDR-TB). 54 million lives were saved through effective diagnosis and treatment, between the years of 2000-2017.
This article by Editorial Board tell us about the world health organization that about 10 million people globally developed active tuberculosis, which is caused by bacterium mycobacterium tuberculosis and that is caused 1.6 million died from the illness. Who has identified big and persistent gaps in discovery and treatment, and another factor is the rise of drug resistant strains that was more difficult to treat, it can be effective new antibiotic that might help save lives among those with the most highly drug resistant strains.
How new treatment has been developed
In February 2000 representatives from universities, industry, governments, donors and others gathered in Cape Town, South Africa, to discuss the need for new TB treatments. The group came up with the Cape Town Declaration which described a way of encouraging the development of new drugs for the treatment. The group still the exists today and is known as the TB Alliance. Some of the member of this group include the American Lung Association, American Society for Tuberculosis Education and Research, American Thoracic Society, Association of the British Pharmaceutical Industry, Bill & Melinda Gates Foundation, Boston Consulting Group, European Commission, Global Forum for Health Research, International Union Against Tuberculosis and Lung Disease, Lupin Laboratories, Médecins Sans Frontières, Medical Research Council of South Africa, Novartis India Ltd, Partners in Health, Research Triangle Institute, Rockefeller Foundation, Royal Netherlands Tuberculosis Association (KNCV), Sequella Global Tuberculosis Foundation, Stop TB Initiative , TDR (Tropical Diseases Research), U.K. International Development Secretary, U.S. Agency for International Development , U.S. Centers for Disease Control, U.S. National Institutes of Health, U.S. National Tuberculosis Center, Wellcome Trust, World Bank , and the World Health Organization. (Alliance, 2019)
The following diagram shows how the various members were connected to form the TB Alliance. On August 14, 2019) the U.S. Food & Drug Administration (FDA) approved the use of Pretomanid, a drug developed by the TB Alliance to help in the treatment of people suffering from highly drug-resistant forms of TB. Pretomanid is used together with bedaquiline and linezolid to from a treatment known as the BPaL regimen.
Conclusion
Recent collaboration between scientists and the development of research networks have resulted in the production of new effective treatments for TB. it is important to get new treatments because the TB kills more than a million people worldwide every year. A number of new drugs have been developed which have been shown to be more effective against TB than isoniazid, a decades old drug which is currently one of the standard treatments. As well as, scientists have a lot of treatment to provide to treat tuberculosis and the scientists tried to developed. Communicating and collaborating to develop to treatment in this report the information about commination and collaboration between scientists to provide a good treatment and how to develop treatment will be providing.
Stuck on your essay?
