Ovarian Cancer essays

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3 Pages 1379 Words
An effective screening method for detection of early-stage ovarian cancer requires a specificity of at least 99.6%, sensitivity of at least 75% and a positive predictive value of at least 10% (Clarke-Pearson DL, 2009). Because of the requirement to have high specificity in order to be considered as a screening tool in the general population, this Is a great challenge....
Ovarian Cancer
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4 Pages 1914 Words
Introduction The advancements in NGS technologies and the emergence of Omics field has led to the development of various approaches in studying cancer. The common approaches to identify molecular mechanisms in cancer include scanning the genome for cancer-specific mutations, exploring differential expression of mRNA through transcriptomics or that of protein through proteomics [Chakraborty S et al. (2018)]. However, limiting the...
Ovarian Cancer
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2 Pages 1126 Words
Introduction Ovarian cancer (OC) is the 9th most common cancer and the 9th most common cause of cancer-related death in women, with an overall 5-year survival of approximately 40%. In 2018, 295,414 new cases of OC were documented worldwide, 184,799 of which resulted in death (1). High-grade serous ovarian carcinoma (HGSOC) is the most common and deadliest subtype of epithelial...
Ovarian Cancer
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2 Pages 1006 Words
An ovary is a reproductive gland part of the female reproductive system that is responsible for producing oocytes and the hormones estrogen and progesterone. An ovum is released from the ovary each month with the intention of meeting sperm in the fallopian tube, traveling to the uterus, and implanting for pregnancy. According to the American Cancer Society, “about 22,240 women...
Ovarian Cancer
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2 Pages 1110 Words
Diagnosis of ovarian cancer is impeded by the absence of symptoms in the early stage hence the disease presents with a high mortality rate. Since the discovery of carcinoembryonic antigen (CEA), cancer antigen 125 (CA125) to the development of multivariate assays (Ova1, ROMA, Overa) that have increased specificity and sensitivity, there has been considerable progress in the discovery of biomarkers...
Ovarian Cancer
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4 Pages 2004 Words
It is usually not possible to know the exact reason why one person develops cancer and others do not. However, studies have examined the reasoning for why certain risk factors may increase or decrease a person’s chances of developing cancer. A few important reasons such as a person’s lifestyle behaviors, environmental and dietary factors, and occupational exposure are contributed to...
Ovarian Cancer
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4 Pages 1685 Words
Common facts about the organ and symptoms Ovaries are an integral organ in the female reproductive system in which ultrasound plays an outstanding role in diagnosing and differentiating many ovarian pathologies. The main function of the ovary is to release a mature oocyte every 28 days and to secrete oestrogen and progesterone for maintaining the reproductive cycle and to support...
Ovarian Cancer
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