Muscular dystrophy is a genetic disease that currently has no cure. There are medical treatments and medications that can help ease symptoms and manage the disease. We will discuss further later what these treatments and medications are and how they can help the patient. Let's first briefly discuss the history of muscular dystrophy and how the disease propagates. Muscular dystrophy comes in various types, one being Duchenne Muscular Dystrophy (DMD), and will be the focus of this discussion. According to...
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The developmental condition that I thought would be the most beneficial to learn to enhance my chiropractic career is muscular dystrophy. Muscular dystrophy is categorized as rare genetic diseases, that displays numerous symptoms, however, the main apparent symptom is loss of muscle function (Do et al. 2018). The abnormality that appears with muscular dystrophy is that abnormal genes interrupt the production of protein affecting the natural process that is essential to developing healthy functional muscle (Mayoclinic, n.d.). The several types...
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Introduction: Muscular dystrophies are defined as a group of heterogeneous group of diseases characterized by muscle weakness (Rahimov et al, 2013). There are different kinds of muscular dystrophy like Duchenne, Becker, Myotonic, Congenital, Emery-Dreifuss, Facioscapulohumeral, Limb-girdle, Distal, and Oculopharyngeal (Table 1). The most common form is Duchenne muscular dystrophy (DMD). 1 in every 3500 to 5000 newborn males worldwide are affected by it. Symptoms of muscle weakness are seen typically between 3 to 7 years of age. Boys suffering from...
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Duchenne’s Muscular Dystrophy is a genetic disorder linked to the X chromosome that is caused by a deficiency in the protein dystrophin (Mendell et al., 1995). This disease weakens skeletal and cardiac muscles, and may pose obstacles when sitting, standing, walking, and speaking. Treatment by myoblast transfer showed promising results in animal trials. This method strives to replace dystrophin through the injection of donor myoblast cells into skeletal muscles. The donor cells are able to replace dystrophin by fusing with...
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Introduction: An ongoing investigation has indicated that CRISPR can be utilized as a generative method that can treat Duchenne muscular dystrophy. Because of an examination in mice, it could be created as a remedial choice for humans Duchenne muscular dystrophy is caused by a defective gene for dystrophin. Duchenne muscular dystrophy occurs in about 1 out of every 3,600 males commonly between 3 to 6 years. As this is an inherited disorder, risks include a family history of Duchenne muscular...
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Rationale A muscular dystrophy is a group of diseases that cause progressive weakness and loss of muscle mass. It is a genetic X-linked recessive inherited disorder which primally effects males. It is passed down through the mother who is a carrier of the gene. Becker Muscular Dystrophy (BMD) is one of the nine different types of Muscular Dystrophy. There is no cure. Muscular Dystrophy is a mutation of one or more genes which interfere with the production of proteins called...
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Inquiry Question: Should funding be allocated towards further research into genome editing as a clinical treatment for Duchenne Muscular Dystrophy? Introduction: Duchenne Muscular Dystrophy is a form of inherited neuromuscular disease found in children, causing progressive degeneration of muscle stability. It is as a result of a mutation in the DMD gene coding for the protein called dystrophin. A mutation is defined as the change in the base sequence of an organism. This mutation is inherited as it is passed...
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