Life is a DNA driven programme and death results from its technical failure. Protein and DNA were evolved naturally from the gas present in the environment of the primitive world. It was the effect of high voltage thunderbolts and asteroid hits on the surface of the earth. Millions of years ago passage of the high voltage energy across the environmental...
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The purpose of this article is to sensitize the clinical genetics community to the issues of discrimination against children with Down syndrome and their families as discrimination represent economic and social coercion, in order to make attempts to provide non directive prenatal genetic counseling and provide postnatal care and counseling. Down syndrome is a genetic chromosome 21 disorder causing developmental...
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First recognized in 1926, ataxia-telangiectasia, otherwise referred to as AT, is an extremely rare and ineluctably progressive disease which slowly denigrates the nervous system. Ataxia–telangiectasia is an autosomal recessive, caused by mutations in the ataxia–telangiectasia mutated gene (ATM), which is best described as a serine/threonine kinase that activates over two dozen proteins involved in controlling cell growth and division. Individuals...
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Abstract An important method used in biology is plasmid purification. What makes this method so important is because a purified plasmid sample is essential for many experiments, including important techniques like DNA sequencing. Purified E.coli plasmid pBR322 using gel electrophoresis and a calibration curve were used in this experiment to quantify the size of the purified plasmid. Examples were examined...
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The origin of DNA fingerprinting was discovered in 1984 by Dr Alec Jeffreys (Jackson and Jackson, 2011, p. 158). Over the decades, with technical developments in genetics, the original DNA fingerprinting procedure has undertaken a variety of modifications and refinements. DNA profiling has become so precise and sensitive that in the United Kingdom it is no longer allowed to be...
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Food insecurity is the lack of access to enough nutritious food, and is an occurrence that hundreds of millions of people face daily (P. Webb, 2006). Genetically modified crops provide great opportunity to improve food quality and to improve yields of crops without increasing the need for fertilisers and pesticides (R. Goodman, 2008). This suggests that genetic modification could help...
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In the late 19th and early 20th century, Britain was seen as one of the strongest empires across the world; and was also spread with an imperialistic attitude which can be seen from the 20 year reign on the Conservatives which was the party of the empire. However, this imperialistic atmosphere within Britain was soon to be stopped by the...
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Germline gene therapy has developed a wide spread of opinions into the regards of its ethics with many very relevant positive and negative opinions being expressed amongst the breakthroughs occurring within its progress. There are lots of varying factors contributing towards these ethics which both overlap and contrast in many ways. The argument on the ethics of this therapy has...
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The reuptake of dopamine within the brain is initiated by proteins referred to as “Dopamine Transporters” (DAT) found in-between neurons. DAT act on the pre-synaptic neurons nerve endings and allows them to absorb the dopamine neurotransmitter, thus terminating the transmission of a message. The reuptake and regulation of dopamine results in a steady and level headed mental state. Dopamine as...
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In the last few decades there has been an increasing interest on how genes affect children’s learning processes and development. Nowadays, researchers are trying to find out what exactly is contributing in education, what are the important outcomes any educational professional should know and how education can be improved. Biological factors are actually being measured in different studies to be...
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Introduction This project will be discussing how DNA evidence has assisted the UK’s criminal justice system in identify defendants that are involved in crimes, and to what extent has it done so? To be able to answer this question, the historical side of DNA evidence will need to be highlighted and what developments have been made since its inception. Another...
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A gene is a nucleotide sequence which dictates the synthesis of a particular RNA or protein molecule. Their control over the produced proteins govern both phenotypical and genetic traits, including susceptibility to diseases like Cystic Fibrosis. Driving gene expression is Central Dogma, a two-step process in which DNA is converted to an intermediate RNA (mRNA) through transcription, then from mRNA...
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Gene Therapy consists of modifying the genes within somatic cells to treat or prevent a disease. The reason this is possible is because genes contain our DNA, which is what decides a huge part of a person and what they look like. When a gene is damaged or missing, it can lead to health issues making gene therapy an option...
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ABSTRACT Inter specific hybridization was made between susceptible greengram variety CO 5 and wild Vigna sp. Crossed seeds were raised in field condition for testing the MYMV incidence. F1 showed dominant resistance reaction against MYMV disease incidence. The field growing F2 populations of C0 5 x wild Vigna sp cross produced a wide range of segregant viz., susceptible, parental and...
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A genome is a segment of DNA that provide the instruction for making specific proteins, which contains the information of a person’s body. A genome information is needed to maintain and build the organism throughout the life. It’s impacts are shown through a person’s hair, eyes, skin, and more. Additionally, the more principle role of the genome is it can...
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A newlywed couple steps into their local geneticist’s office excitedly. Today is the day they have been looking forward to for years. With a loan from the bank, genetic insurance, and financial aid from their parents, the couple has finally collected enough money to design their perfect child. As future parents, they must ensure a perfect life for their first...
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Abstract In this Research Paper, the reader will be able to learn what is the meaning, the purpose, and how DNA databases are used. DNA databases are not just lists of DNA collected by law enforcement from individuals and crime scenes, and they are also created by profit and non-profit organizations. This paper also has my personal opinion as the...
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There are several physiological changes that occur during normal pregnancy, hypercoaggulabilty state is one of them in which some coagulation factors increased in blood in harmony with decreased blood level of others. These changes are needed for normal fetal growth and development with complete return to the normal physiological state after labor and purperium without leaving any harm to the...
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Abstract Some real threats such as global warming, air pollution have made the necessity of thinking about a renewable power resource, among the different methods Microbial fuel cells (MFCs) as a method to produce electricity from the oxidation of organic molecules by biocatalysts, has been proposed. In MFC reactors, electrons generated by biological oxidation reactions are harvested by the anode....
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ABSTRACT The invention of a robust gene-editing tool, Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) which is cost efficient and quite simple to use, made the birth of humans genetically modified in in-vitro fertilization ( IVF) center a theoretical possibility. According to the Center for Genetics and Society, a non-profit-making data and public affairs organization, human genetic engineering is the...
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The cloning process is taking cells from an individual and replicating genes or DNA. In the process of cloning the gene is entered in the plasmid, which is a piece of the DNA (Overview: DNA cloning, 2019). There are four steps into the cloning process (Eric J. Simon, 2016). The steps are as follow; Put the gene in the plasmid...
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In 1940, biologist had a hard time accepting DNA as genetic information due to its chemistry (The Structure and Function of DNA, n.d.). DNA is a nucleic acid and is where genetic information is stored in a molecule to build and maintain an organism (DNA structure and function, 2014). DNA is known as the molecule of heredity (Gaughan, 2019). The...
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Everything in the universe is made of plenty of different types of atoms such as hydrogen, oxygen, nitrogen, and so on, but plenty of them do not have life; for example, they can be clothes, machines, papers, and so on. Even though they do not have life, they are very useful for human beings’ life, so we need to be...
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In Australia Gene editing technology is fast on the rise and has large potential for change in the future and therefore must be legislated and monitored with great care for the benefit of Australia and its inhabitants. Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) allows scientists to essentially copy and paste DNA in humans, animals,bacteria and plants. The benefits of...
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Introduction Sequencing is the arrangement of nucleotides. It includes different technologies that are used to arrange or know the arrangement of adenine, guanine, cytosine and thymine. It is used for molecular study of genomes and protiens that are encoded. Information that's obtained by sequencing help us to understand the changes in genome of an organism. Even by sequencing we can...
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Abstract Through the lens of this experiment, it shows that the gene Rfp encoding, a mutant of the red fluorescent protein - a product of the coral Discosoma striata, AmilCp encoding for the blue chromoprotein from Acropora millespora were duplicated into a pTTQ18 plasmid vector. Accompanied with the amplified PCR of the DNA fragments encoding carrying the Rfp and AmilCp...
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Abstract The exploitation of shark species to satisfy the high market demand is now becoming a worldwide concern since the numbers for many species of these apex predators are now declining at an alarming rate. Shark DNA extracted from shark samples collected from the Australian fisheries management, amplified and used for identification. Although there are different methods of identifying a...
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Abstract DNA cloning and expression vectors are the modern-day mainstays for molecular biology studies. In Spite Of advances in synthetic biology and modern techniques, researchers around the world still uses the standard way of DNA cloning, using plasmids and reporter proteins for selecting possible recombinant DNA. The coloured properties of blue coral chromoproteins (AmilCP) and red fluorescent protein (Rfp), from...
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In current research, genome editing has become an essential and a very powerful tool that holds the capacity to tackle extreme biological problems by purposeful alteration of a specific DNA segment in a cell. In late 2018, Jiankui He (JK), a Chinese researcher revealed his experiments to confer resistance against HIV by conducting germline genome editing on human embryos. JK...
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Gene editing in agriculture Gene editing involves making distinct changes in the DNA sequence of a plant/animal cell creating a desired genetic make-up. Gene editing is a powerful tool for genome editing which requires high specificity and uses enzymes known as nucleases which cut the DNA at the desired site while another sequence is inserted to replace the cut sequence...
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